Parkes Weber syndrome
MONDO:0700325A rare congenital complex vascular malformation syndrome characterized by overgrowth of a limb (most commonly a leg) involving bones and soft tissue, in association with capillary malformations usually in the form of port-wine stains and multiple arteriovenous fistulas with high-flow arteriovenous shunting. The latter can also lead to other severe complications including abnormal bleeding and heart failure. Lymphatic malformations may also be present.
Also known as: PWS
7 clinical trials for this condition and its sub-types.
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Electric shocks boost drug to shrink blood vessel tangles
Disease control Not yet recruitingThis phase 2 trial tests a new treatment called bleomycin electrosclerotherapy (BEST) for low-flow vascular malformations—abnormal clusters of blood or lymph vessels. The approach combines an injected drug (bleomycin) with brief electrical pulses to make the drug work better. Res…
Phase: PHASE2 • Sponsor: Institute of Oncology Ljubljana • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New hope for rare blood vessel disorders: everolimus trial launches
Disease control Not yet recruitingThis phase 2 trial tests the drug everolimus in 67 people with vascular anomalies (abnormal blood vessels) that haven't responded to standard treatments. The goal is to shrink the lesions and improve symptoms. Participants take everolimus daily for 6 months, with doses adjusted b…
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC