Parkes Weber syndrome
MONDO:0700325A rare congenital complex vascular malformation syndrome characterized by overgrowth of a limb (most commonly a leg) involving bones and soft tissue, in association with capillary malformations usually in the form of port-wine stains and multiple arteriovenous fistulas with high-flow arteriovenous shunting. The latter can also lead to other severe complications including abnormal bleeding and heart failure. Lymphatic malformations may also be present.
Also known as: PWS
7 clinical trials for this condition and its sub-types.
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Could a transplant drug shrink Children's birthmarks?
Disease control CompletedThis study tested the drug sirolimus (rapamycin) in 63 children aged 6 to 18 with large, complicated slow-flow vascular malformations (abnormal blood or lymph vessels). Each child had an observation period followed by 4 to 8 months of sirolimus treatment. The main goal was to see…
Phase: PHASE2 • Sponsor: University Hospital, Tours • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New contrast dye aims to sharpen MRI images of body lesions
Diagnosis CompletedThis study tests a new contrast agent called HRS-9231 for MRI scans of body parts (excluding the brain and spine). The goal is to see if it makes abnormal blood vessels or lesions show up as clearly as a standard contrast agent. About 309 adults who already need a contrast MRI ar…
Phase: PHASE3 • Sponsor: Shanghai Shengdi Pharmaceutical Co., Ltd • Aim: Diagnosis
Last updated Jul 02, 2026 00:00 UTC
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French study tracks port wine stains in kids to uncover hidden risks
Knowledge-focused CompletedThis study followed 150 children aged 2 to 12 who have a port wine stain on a leg. Researchers tracked how the stain changes as the child grows, and whether it leads to problems like blood vessel issues or bone growth differences. The goal was to learn more about the condition an…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC