Pantothenate kinase-associated neurodegeneration

Pantothenate kinase-associated neurodegeneration (PKAN) is the most common type of neurodegeneration with brain iron accumulation (NBIA), a rare neurodegenerative disorder characterized by progressive extrapyramidal dysfunction (dystonia, rigidity, choreoathetosis), iron accumulation on the brain and axonal spheroids in the central nervous system.

Also known as: brain iron accumulation type I syndrome, Hallervorden-Spatz disease, Hallervorden-Spatz syndrome, NBIA1, PKAN, neurodegeneration with brain iron accumulation 1, neurodegeneration with brain iron accumulation type 1, pantothenate kinase-associated neurodegeneration

16 clinical trials for this condition and its sub-types.