Non-immune hydrops fetalis
MONDO:0009369Non-immune hydrops fetalis (NIHF), a form of HF, is a severe fetal condition defined as the excessive accumulation of fetal fluid within the fetal extravascular compartments and body cavities, and is the end-stage of a wide variety of disorders.
Also known as: non-immune HF, non-immune fetal edema, non-immune fetal hydrops, non-immune foetal hydrops, non-immune foetal oedema, Haemoglobin H hydrops fetalis syndrome, Hemoglobin H hydrops fetalis syndrome, NIHF
9 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
New pill may cut transfusions for thalassemia patients
Disease control OngoingThis phase 3 study tests whether mitapivat, an oral medication, can safely reduce the number of blood transfusions needed by adults with transfusion-dependent alpha- or beta-thalassemia. Participants receive either mitapivat or a placebo for 48 weeks. The main goal is to see if m…
Phase: PHASE3 • Sponsor: Agios Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
-
Genetic sleuthing aims to solve mysteries of fetal hydrops
Knowledge-focused OngoingThis national study is looking at 500 babies and fetuses with non-immune hydrops fetalis or other birth defects to find hidden genetic causes. Researchers are using a detailed genetic test called exome sequencing to look for DNA changes that might explain these conditions. The go…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
-
Gene hunt aims to solve mysterious fetal swelling disorder
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks for genetic causes of non-immune hydrops fetalis, a condition where fluid builds up abnormally in a fetus, leading to high risks of stillbirth or death. Researchers will use whole genome sequencing on 500 affected fetuses or newborns and their parents. The goal i…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC