Gene hunt aims to solve mysterious fetal swelling disorder
NCT ID NCT05528796
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks for genetic causes of non-immune hydrops fetalis, a condition where fluid builds up abnormally in a fetus, leading to high risks of stillbirth or death. Researchers will use whole genome sequencing on 500 affected fetuses or newborns and their parents. The goal is to find hidden genetic diseases to improve prenatal care and outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better diagnosis and targeted care for pregnancies affected by non-immune hydrops fetalis, potentially improving survival and outcomes.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find causes for all cases, and results may take years to impact clinical practice.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of California, San Francisco
San Francisco, California, 94143, United States
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Other studies related to the condition(s) this trial covers.