Genetic sleuthing aims to solve mysteries of fetal hydrops

NCT ID NCT03412760

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This national study is looking at 500 babies and fetuses with non-immune hydrops fetalis or other birth defects to find hidden genetic causes. Researchers are using a detailed genetic test called exome sequencing to look for DNA changes that might explain these conditions. The goal is to learn more about what causes these problems and how different genetic changes affect outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better understand the genetic causes of hydrops fetalis and birth defects, leading to improved diagnosis and counseling for families.

What could go wrong

This is an observational study, not a treatment trial. It may not directly change outcomes for participants, and the genetic findings may not apply to all cases.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Congenital Abnormalities hydrops fetalis non-immune hydrops fetalis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States