Neurodegenerative disease

Part of

Sub-types of Neurodegenerative disease

• Tauopathy 24 trials · 1,190 incl. sub-types
  2 sub-types

  • Alzheimer disease 1,184 trials Sub-types →
  • Argyrophilic grain disease 0 trials
• Demyelinating disease 27 trials · 931 incl. sub-types
  8 sub-types

  • Demyelinating disease of central nervous system 4 trials · 860 incl. sub-types Sub-types →
  • Polyradiculoneuropathy 1 trial · 64 incl. sub-types Sub-types →
  • Demyelinating polyneuropathy 2 trials · 62 incl. sub-types Sub-types →
  • Acute disseminated encephalomyelitis 7 trials · 8 incl. sub-types Sub-types →
  • Central pontine myelinolysis 2 trials
  • Balo concentric sclerosis 0 trials
  • Schilder disease 0 trials
  • Boylan dew greco syndrome 0 trials
• Inherited neurodegenerative disorder 10 trials · 807 incl. sub-types
  82 sub-types

  • Frontotemporal dementia 132 trials · 178 incl. sub-types Sub-types →
  • Hereditary motor neuron disease 1 trial · 169 incl. sub-types Sub-types →
  • Hereditary cerebellar ataxia 0 trials · 116 incl. sub-types Sub-types →
  • Huntington disease and related disorders 0 trials · 91 incl. sub-types Sub-types →
  • Progressive supranuclear palsy 73 trials · 77 incl. sub-types Sub-types →
  • Leukodystrophy 6 trials · 72 incl. sub-types Sub-types →
  • Familial Alzheimer disease 13 trials · 55 incl. sub-types Sub-types →
  • Hereditary spastic paraplegia 27 trials · 33 incl. sub-types Sub-types →
  • Hereditary optic atrophy 6 trials · 23 incl. sub-types Sub-types →
  • Neuronal ceroid lipofuscinosis 6 trials · 23 incl. sub-types Sub-types →
  • GM2 gangliosidosis 14 trials · 19 incl. sub-types Sub-types →
  • Kennedy disease 19 trials
  • Corticobasal syndrome 19 trials
  • Frontotemporal dementia with motor neuron disease 13 trials · 19 incl. sub-types Sub-types →
  • Posterior cortical atrophy 11 trials
  • Chediak-Higashi syndrome 9 trials
  • Neurodegeneration with brain iron accumulation 1 trial · 8 incl. sub-types Sub-types →
  • APP-related brain and vascular amyloidosis 0 trials · 5 incl. sub-types Sub-types →
  • Frontotemporal dementia and/or amyotrophic lateral sclerosis 0 trials · 5 incl. sub-types Sub-types →
  • Inherited Creutzfeldt-Jakob disease 5 trials
  • TUBB4A-related neurologic disorder 4 trials Sub-types →
  • Fatal familial insomnia 4 trials
  • Mitochondrial DNA depletion syndrome 4a 3 trials
  • Alzheimer disease 17 1 trial
  • Alzheimer disease 18 1 trial
  • Ataxia-telangiectasia-like disorder 1 trial Sub-types →
  • Developmental and epileptic encephalopathy, 35 1 trial
  • Neurodegeneration, childhood-onset, stress-induced, with variable ataxia and seizures 1 trial
  • Neurodegenerative syndrome due to cerebral folate transport deficiency 1 trial
  • Neuronal intranuclear inclusion disease 1 trial
  • Recurrent metabolic encephalomyopathic crises-rhabdomyolysis-cardiac arrhythmia-intellectual disability syndrome 1 trial
  • DCTN1-related neurodegeneration 0 trials Sub-types →
  • Huntington disease-like 1 0 trials
  • Huntington disease-like 2 0 trials
  • ITM2B amyloidosis 0 trials Sub-types →
  • PEHO syndrome 0 trials
  • PRKAR1B-related neurodegenerative dementia with intermediate filaments 0 trials
  • X-linked neurodegenerative syndrome, Bertini type 0 trials
  • X-linked neurodegenerative syndrome, Hamel type 0 trials
  • Agenesis of the corpus callosum with peripheral neuropathy 0 trials
  • Amyotrophic lateral sclerosis-parkinsonism-dementia complex 0 trials
  • Angioid streaks of choroid 0 trials
  • Attenuated Chédiak-Higashi syndrome 0 trials
  • Autosomal recessive cerebral atrophy 0 trials
  • Boylan dew greco syndrome 0 trials
  • Cerebellar ataxia-hypogonadism syndrome 0 trials Sub-types →
  • Cerebral sclerosis similar to Pelizaeus-Merzbacher disease 0 trials
  • Combined oxidative phosphorylation deficiency 29 0 trials
  • Deafness dystonia syndrome 0 trials
  • Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome 0 trials
  • Dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities 0 trials
  • Early-childhood-onset neurodegeneration with retinitis pigmentosa, sensorineural hearing loss, and demyelinating peripheral neuropathy 0 trials
  • Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome 0 trials
  • Encephalopathy due to beta-mercaptolactate-cysteine disulfiduria 0 trials
  • Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy 0 trials Sub-types →
  • Facial onset sensory and motor neuronopathy 0 trials
  • Fatal post-viral neurodegenerative disorder 0 trials
  • Ferro-cerebro-cutaneous syndrome 0 trials
  • Hereditary sensory neuropathy-deafness-dementia syndrome 0 trials
  • Hypotonia, infantile, with psychomotor retardation and characteristic facies 0 trials Sub-types →
  • Infantile cerebellar-retinal degeneration 0 trials
  • Infantile-onset axonal motor and sensory neuropathy-optic atrophy-neurodegenerative syndrome 0 trials
  • Microphthalmia-brain atrophy syndrome 0 trials
  • Myoclonic cerebellar dyssynergia 0 trials
  • Neurodegeneration and seizures due to copper transport defect 0 trials
  • Neurodegeneration with ataxia and late-onset optic atrophy 0 trials
  • Neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset 0 trials
  • Neurodegeneration with developmental delay, early respiratory failure, myoclonic seizures, and brain abnormalities 0 trials
  • Neurodegeneration, childhood-onset, with ataxia, tremor, optic atrophy, and cognitive decline 0 trials
  • Neurodegeneration, childhood-onset, with cerebellar ataxia and cognitive decline 0 trials
  • Neurodegeneration, childhood-onset, with cerebellar atrophy 0 trials
  • Neurodegeneration, childhood-onset, with hypotonia, respiratory insufficiency, and brain imaging abnormalities 0 trials
  • Neurodegeneration, childhood-onset, with multisystem involvement due to mitochondrial dysfunction 0 trials
  • Neurodegeneration, childhood-onset, with progressive microcephaly 0 trials
  • Neurodegeneration, early-onset, with choreoathetoid movements and microcytic anemia 0 trials
  • Neurodegeneration, infantile-onset, biotin-responsive 0 trials
  • Neurodegenerative disorder with cerebellar and caudate atrophy 0 trials
  • Neurodegenerative disorder, X-linked, female-restricted, with parkinsonism and cognitive impairment 0 trials
  • Psychomotor regression-oculomotor apraxia-movement disorder-nephropathy syndrome 0 trials
  • Radiation sensitivity/chromosome instability syndrome, autosomal dominant 0 trials
  • Severe neurodegenerative syndrome with lipodystrophy 0 trials
  • Striatonigral degeneration 0 trials Sub-types →
• Motor neuron disorder 69 trials · 506 incl. sub-types
  4 sub-types

  • Amyotrophic lateral sclerosis 327 trials · 341 incl. sub-types Sub-types →
  • Hereditary motor neuron disease 1 trial · 169 incl. sub-types Sub-types →
  • Acquired motor neuron disease 0 trials · 39 incl. sub-types Sub-types →
  • Madras motor neuron disease 0 trials
• Synucleinopathy 18 trials · 237 incl. sub-types
  2 sub-types

  • Lewy body dementia 130 trials
  • Multiple system atrophy 110 trials · 119 incl. sub-types Sub-types →
• Cerebellar degeneration 6 trials · 150 incl. sub-types
  2 sub-types

  • Cerebellar ataxia 40 trials · 144 incl. sub-types Sub-types →
  • Paraneoplastic cerebellar degeneration 1 trial
• Primary progressive aphasia 42 trials · 71 incl. sub-types
  2 sub-types

  • GRN-related frontotemporal lobar degeneration with Tdp43 inclusions 6 trials · 47 incl. sub-types Sub-types →
  • Logopenic progressive aphasia 15 trials
• Cerebral degeneration 0 trials · 61 incl. sub-types
  2 sub-types

  • Pick disease 35 trials
  • Corticobasal degeneration disorder 28 trials
• Secondary Parkinson disease 9 trials
  1 sub-type

  • Postencephalitic Parkinson disease 0 trials
• Neuroaxonal dystrophy 1 trial · 9 incl. sub-types
  2 sub-types

  • Neurodegeneration with brain iron accumulation 1 trial · 8 incl. sub-types Sub-types →
  • Neuroaxonal dystrophy renal tubular acidosis 0 trials
• Primary progressive apraxia of speech 2 trials
• Marchiafava-Bignami disease 1 trial
• Human prion disease 1 trial
  4 sub-types

  • Acquired human prion disease 0 trials
  • Kuru 0 trials
  • Sporadic fatal insomnia 0 trials
  • Variably protease-sensitive prionopathy 0 trials
• Brachial amyotrophic diplegia 0 trials
• Choroidal sclerosis 0 trials
  4 sub-types

  • Angioid streaks of choroid 0 trials
  • Diffuse secondary choroid atrophy 0 trials
  • Hereditary choroidal atrophy 0 trials Sub-types →
  • Senile atrophy of choroid 0 trials
• Eyelid degenerative disorder 0 trials
• Hypertrophic olivary degeneration 0 trials
• Infantile bilateral striatal necrosis 0 trials
  2 sub-types

  • Familial infantile bilateral striatal necrosis 0 trials Sub-types →
  • Sporadic infantile bilateral striatal necrosis 0 trials
• Olivopontocerebellar atrophy 0 trials
• Primary progressive freezing gait 0 trials
• Senile degeneration of brain 0 trials
• Superficial siderosis 0 trials