Moderate heart failure
MONDO:0005256Heart failure characterized by marked limitation in activity due to symptoms, even during less-than-ordinary activity, e.g. walking short distances (20b100 m). Patients with moderate heart failure are comfortable only at rest.
43 clinical trials for this condition and its sub-types.
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Smart algorithm aims to improve heart failure care
Disease control CompletedThis study tested a new way to manage heart failure using a small heart monitor (Reveal LINQ) and a special algorithm. The goal was to see if this approach could safely guide treatment and improve outcomes for people with moderate heart failure. 826 participants with NYHA class I…
Phase: NA • Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Heart failure patients get better meds in special clinic
Disease control CompletedThis study tested whether a special clinic (GDMT Clinic) helps heart failure patients get the right medications compared to usual care. About 300 adults with heart failure took part over 12 weeks. The clinic aimed to improve medication use, health status, and heart function.
Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Wireless lung sensor could keep heart failure patients out of hospital
Disease control CompletedThis study tested a device called the Cordella™ Heart Failure System in 15 people with advanced heart failure. The system includes a small sensor implanted in the lung artery that measures pressure, sending data to doctors remotely. The goal was to see if it is safe and accurate,…
Phase: NA • Sponsor: Endotronix, Inc. • Aim: Disease control
Last updated Jun 26, 2026 12:49 UTC
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Heart MRI breakthrough: new scan could replace needle biopsy for rare heart disease
Diagnosis CompletedThis study tested whether a special type of heart MRI, called T1 mapping, can accurately diagnose cardiac amyloidosis—a condition where abnormal proteins build up in the heart muscle. Researchers studied 112 older adults with heart failure and thickened heart walls. They compared…
Sponsor: University of Leipzig • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Pacemaker tweak may ease heart failure by calming nerves
Symptom relief CompletedThis study tested a modified pacemaker in 34 people with heart failure (NYHA class II or III). The device delivers special pacing signals to reduce overactive sympathetic nerve activity, which can strain the heart. Researchers measured changes in arterial elastance, a sign of rel…
Sponsor: BackBeat Medical Inc • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Heart failure drug use tracked in 13,660 remote monitoring patients
Knowledge-focused CompletedThis completed observational study looked at how often heart failure patients in a French nationwide remote monitoring program were prescribed SGLT2 inhibitors between 2021 and 2024. Researchers analyzed data from over 13,600 adults to see how prescription rates changed over time…
Sponsor: Satelia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Heart failure drug vericiguat under Real-World scrutiny in japan
Knowledge-focused CompletedThis study analyzed data from nearly 5,000 Japanese patients with chronic heart failure who started taking vericiguat as part of their regular care. Researchers tracked outcomes like hospital stays and deaths over one year to see how the drug performs in everyday practice. The go…
Sponsor: Bayer • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC