Meningococcal meningitis
MONDO:0018059An acute bacterial disease caused by Neisseria meningitides that presents usually, but not always, with a rash (non blanching petechial or purpuric rash), progressively developing signs of meningitis (fever, vomiting, headache, photophobia, and neck stiffness) and later leading to confusion, delirium and drowsiness. Neck stiffness and photophobia are often absent in infants and young children who may manifest nonspecific signs such as irritability, inconsolable crying, poor feeding, and a bulging fontanel. Meningococcal meningitis may also present as part of early or late onset sepsis in neonates. The disease is potentially fatal. Surviving patients may develop neurological sequelae that include sensorineural hearing loss, seizures, spasticity, attention deficits and intellectual disability.
24 clinical trials for this condition and its sub-types.
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New meningitis vaccine enters first human tests
⭐️ VACCINE ⭐️ Not yet recruitingThis early-stage trial is testing a new vaccine designed to protect against several types of meningococcal bacteria, which can cause meningitis and bloodstream infections. Researchers will enroll 150 healthy people aged 2 to 59 to check the vaccine's safety and how well it trigge…
Phase: PHASE1 • Sponsor: Sinovac Life Sciences Co., Ltd. • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:00 UTC
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Rapid brain infection test could slash unnecessary antibiotic use
Diagnosis Not yet recruitingThis study looks at whether a quick diagnostic test (BioFire FilmArray) can accurately predict the cause of meningitis or encephalitis in 182 adults. Participants with symptoms like fever, headache, or confusion will have their spinal fluid tested. The goal is to see if the test …
Phase: NA • Sponsor: Federal University of Health Science of Porto Alegre • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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Can we predict who survives meningitis? a new study seeks answers
Knowledge-focused Not yet recruitingThis study looks at the medical records of 300 people treated for meningitis at a hospital in Sohag, Egypt, to understand what factors influence their chances of recovery. Researchers will review past cases and follow new patients for a year, tracking who survives, who recovers f…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Aug 18, 2026 05:00 UTC
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Could a single meningitis shot protect for years? a study investigates
Knowledge-focused Not yet recruitingThis study follows 180 children who received a meningitis vaccine (ACYW135 conjugate) years ago to see if their immune protection lasts. Researchers will measure antibody levels in blood samples taken 3 and 5 years after vaccination. The goal is to understand how long immunity pe…
Sponsor: CanSino Biologics Inc. • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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New study uses DNA to track hidden gonorrhea in partners
Knowledge-focused Not yet recruitingThis study will recruit 100 sexual partners of people diagnosed with gonorrhea. Researchers will take an extra throat swab to analyze all the bacteria and their genes using a technique called metagenomics. The goal is to find hidden infections, antibiotic resistance, and see how …
Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC