Meniere disease
MONDO:0007972A disease of the inner ear (labyrinth) that is characterized by fluctuating sensorineural hearing loss; tinnitus; episodic vertigo; and aural fullness. It is the most common form of endolymphatic hydrops.
Also known as: Meniere disease, Meniere's disease
30 clinical trials for this condition and its sub-types, 16 tagged with Meniere disease itself.
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Sub-types of Meniere disease
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Active cochlear Meniere disease 0 trials
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Active vestibular Meniere disease 0 trials
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New hope for hearing loss? drug targets inner ear inflammation
Disease control Recruiting nowThis phase 2 trial tests whether anakinra (Kineret), an anti-inflammatory drug, can improve hearing in people with Meniere's disease or autoimmune inner ear disease who cannot take steroids. About 57 participants will receive daily injections of anakinra or a placebo for 42 days,…
Phase 2 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Could a common antidepressant and seizure drug tame Meniere's vertigo?
Symptom relief Recruiting nowThis study tests whether a combination of two existing drugs, nortriptyline and topiramate, can reduce vertigo and other symptoms in people with Meniere's disease. Forty adults with active Meniere's will take the drugs or a placebo for 8 weeks. The goal is to see if this approach…
Phase 4 • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Neck mobilization may ease Meniere's dizziness
Symptom relief Recruiting nowThis study tests whether adding neck therapy (cervical mobilization) to standard balance exercises can reduce dizziness and improve balance in people with Meniere's disease. 33 adults with Meniere's will be split into three groups: one getting only their usual medication, one add…
Sponsor: Abant Izzet Baysal University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Scientists dive deep into mysterious hearing fluctuations
Knowledge-focused Recruiting nowThis study aims to better understand disorders that cause hearing to fluctuate, such as Meniere's disease. Researchers will use advanced MRI scans and blood tests to look for biomarkers linked to hearing changes. The goal is to identify different types of these disorders and pave…
Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Scientists hunt for genetic clues to Menière's disease
Knowledge-focused Recruiting nowThis study aims to uncover genetic and biological differences between people with Menière's disease, those with vestibular migraine, and healthy individuals. Researchers will analyze blood samples from 250 participants to look for specific gene variations and biohumoral factors. …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Sleep troubles may worsen vertigo in Ménière's patients
Knowledge-focused Recruiting nowThis study looks at whether sleep disorders make vertigo worse for people with Ménière's disease, a condition that causes hearing loss, ringing in the ears, and dizziness. Researchers will track 100 adults to see if those with more severe vertigo also have more sleep problems. Th…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC