New hope for hearing loss? drug targets inner ear inflammation
NCT ID NCT03587701
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether anakinra (Kineret), an anti-inflammatory drug, can improve hearing in people with Meniere's disease or autoimmune inner ear disease who cannot take steroids. About 57 participants will receive daily injections of anakinra or a placebo for 42 days, followed by another 42-day period. The study measures hearing improvements and word recognition over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- anakinra (Kineret)
- What this could lead to
- If it works, this could offer a new treatment option for people with Meniere's or autoimmune inner ear disease who cannot use steroids, potentially improving hearing and reducing symptoms.
- What could go wrong
- This is a small, early phase 2 trial with only 57 participants. It may not show a clear benefit, and anakinra can cause injection site reactions or increase infection risk. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for AUTOIMMUNE INNER EAR DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northwell Health, Hearing& Speech Center
RECRUITINGNew Hyde Park, New York, 11042, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Wearable eye-tracker aims to catch dizziness in the act
- Could a new drug quiet the ringing and dizziness of Meniere's disease?
- New MRI scan could diagnose Meniere's disease without needle dye
- Scientists hunt for genetic clues to Menière's disease
- Scientists dive deep into mysterious hearing fluctuations
- Hope for Meniere's sufferers: new drug enters final testing phase