New hope for hearing loss? drug targets inner ear inflammation
NCT ID NCT03587701
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether anakinra (Kineret), an anti-inflammatory drug, can improve hearing in people with Meniere's disease or autoimmune inner ear disease who cannot take steroids. About 57 participants will receive daily injections of anakinra or a placebo for 42 days, followed by another 42-day period. The study measures hearing improvements and word recognition over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
anakinra (Kineret)
What this could lead to
If it works, this could offer a new treatment option for people with Meniere's or autoimmune inner ear disease who cannot use steroids, potentially improving hearing and reducing symptoms.
What could go wrong
This is a small, early phase 2 trial with only 57 participants. It may not show a clear benefit, and anakinra can cause injection site reactions or increase infection risk. Results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Northwell Health, Hearing& Speech Center
RECRUITINGNew Hyde Park, New York, 11042, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••