Membranous glomerulonephritis
MONDO:0005376A slowly progressive inflammation of the glomeruli characterized by immune complex deposits at the glomerular basement membrane, resulting in a thickened membrane, and nephrotic syndrome.
Also known as: membranous Glomerulonephropathy, membranous nephropathy
85 clinical trials for this condition and its sub-types.
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Broader categories
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Molecular map may guide treatment for mysterious inflammatory illnesses
Disease control CompletedThis study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New antibody drug shows promise for tough kidney disease
Disease control CompletedThis study tested a new drug, MIL62, in 94 adults with primary membranous nephropathy, a serious kidney condition. The goal was to see if MIL62 is safe and can help reduce protein in the urine better than the standard drug cyclosporine. Participants received either MIL62 or cyclo…
Phase: PHASE1, PHASE2 • Sponsor: Beijing Mabworks Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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Sweat sensor could replace needles for kidney patients
Diagnosis CompletedThis study tested a new wearable patch that collects sweat to measure sodium and creatinine levels, which are important for monitoring kidney health and dehydration. Five adults with kidney disease wore the patch while their sweat was analyzed using a special light-based techniqu…
Phase: NA • Sponsor: Korea University • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC
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New PET tracer aims to light up hidden infections
Diagnosis CompletedThis early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Study explores how family and friends impact caregiver health
Knowledge-focused CompletedThis completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Blood test may guide treatment for relapsed kidney disease
Knowledge-focused CompletedThis completed lab study took blood samples from 20 adults with relapsed membranous nephropathy, a kidney condition. Researchers tested different immune-modulating drugs on the blood cells to see how they affect the balance of Th17 and Treg immune cells. The goal is to find which…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Simple blood test could spot kidney patients at risk of failure
Knowledge-focused CompletedThis study looks at a new blood test that measures specific antibodies in people with membranous nephropathy, an autoimmune kidney disease. The test aims to predict which patients are more likely to develop kidney failure. Researchers will follow 52 adults over time to see if the…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Blood cell clues may explain why some kidney patients relapse
Knowledge-focused CompletedThis study looks at blood samples from 48 people with membranous nephropathy, a kidney disease. Researchers used a special test to measure immune cells (B cells) that target a protein called PLA2R. The goal is to see how these cells change after treatment with B-cell depleting dr…
Phase: NA • Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Blood cell study may unlock kidney disease secrets
Knowledge-focused CompletedThis study looked at immune cells (T and B cells) in the blood of 44 people with a kidney disease called membranous nephropathy. Researchers wanted to see how these cells relate to treatment response and disease relapse. They also measured specific antibodies linked to the diseas…
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Worldwide kidney study tracks 6,000 patients to unlock disease secrets
Knowledge-focused CompletedThis study followed nearly 6,000 people with kidney disease from around the world. Researchers collected routine test results like kidney function and protein in urine to better understand how the disease progresses. The goal was to gather information, not to test a new treatment…
Sponsor: The George Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC