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Melorheostosis

MONDO:0007970

Melorheostosis is a rare connective tissue disorder characterized by a sclerosing bone dysplasia, usually limited to one side of the body (rarely bilateral), that manifests with pain, stiffness, joint contractures and deformities.

Also known as: melorheostosis, isolated, somatic mosaic, Mel, melorheostosis, isolated

38 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Musculoskeletal system disorder (196) Hereditary disease (172) Bone disorder (47) Human disease (14) Osteopetrosis (6) Bone remodeling disease (5) Skeletal system disorder (4) Disease of genetic or genomic mechanism (2) Osteosclerosis (1)

Trials to join now! 18 Not yet recruiting 6 Not yet finished but already full! 5 Completed 8 Terminated 1

Scientists gather leftover surgical tissue to unlock secrets of bone disease

Knowledge-focused Terminated

This study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …

Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused

Last updated Jun 27, 2026 07:52 UTC