Macroglossia
MONDO:0015496The presence of an excessively large tongue, which may be congenital or may develop as a result of a tumor or edema due to obstruction of lymphatic vessels, or it may occur in association with hyperpituitarism or acromegaly. It also may be associated with malocclusion because of pressure of the tongue on the teeth. (From Jablonski, Dictionary of Dentistry, 1992)
Also known as: enlarged tongue, giant tongue
2 clinical trials for this condition and its sub-types.
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Broader categories
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Experimental antibody shows promise for rare amyloid disease
Disease control CompletedThis phase II trial tested the drug isatuximab in 43 patients with AL amyloidosis that had come back or stopped responding to treatment. Isatuximab is a monoclonal antibody that may help stop abnormal protein buildup. The study measured how well the drug reduced disease markers a…
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 26, 2026 15:04 UTC
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Jaw implants aim to boost life quality after surgery
Symptom relief CompletedThis study looked at how well Global D implants work for orthognathic (jaw) surgery and whether they improve patients' quality of life. 198 people who had their first jaw surgery received these implants. Researchers measured quality of life before and after surgery using a specia…
Sponsor: Global D • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC