Liver and intrahepatic bile duct neoplasm
MONDO:0024477A benign or malignant neoplasm that affects the liver parenchyma or intrahepatic bile ducts. Representative examples of benign neoplasms include hepatocellular adenoma, and bile duct adenoma. Representative examples of malignant neoplasms include hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and lymphoma.
Also known as: epithelial hepatic and intrahepatic bile duct neoplasm, hepatic and intrahepatic bile duct neoplasm, liver and intrahepatic bile duct epithelial neoplasm, liver and intrahepatic bile duct neoplasm, liver neoplasm, liver neoplasm (disease), liver tumor, liver tumour
3102 clinical trials for this condition and its sub-types, 78 tagged with Liver and intrahepatic bile duct neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Liver and intrahepatic bile duct neoplasm
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Liver cancer 255 trials · 1,708 incl. sub-types
5 sub-types
- Carcinoma of liver and intrahepatic biliary tract 36 trials · 1,461 incl. sub-types Sub-types →
- Biliary tract cancer 244 trials · 618 incl. sub-types Sub-types →
- Liver sarcoma 1 trial · 10 incl. sub-types Sub-types →
- Liver lymphoma 1 trial Sub-types →
- Calcifying nested epithelial stromal tumor of the liver 0 trials
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Biliary tract neoplasm 31 trials · 627 incl. sub-types
2 sub-types
- Biliary tract cancer 244 trials · 618 incl. sub-types Sub-types →
- Bile duct neoplasm 41 trials · 472 incl. sub-types Sub-types →
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Liver hemangioma 6 trials
1 sub-type
- Liver cavernous hemangioma 0 trials
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Hepatocellular adenoma 2 trials
1 sub-type
- Hepatic adenomas, familial 0 trials
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Hepatic angiomyolipoma 0 trials
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Hepatic granuloma 0 trials
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Liver adenomatosis 0 trials
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Liver leiomyoma 0 trials
1 sub-type
- Extrahepatic bile duct leiomyoma 0 trials
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Liver lipoma 0 trials
1 sub-type
- Extrahepatic bile duct lipoma 0 trials
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Liver mesenchymal hamartoma 0 trials
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Liver solitary fibrous tumor 0 trials
Most studied deeper sub-types
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Can a cancer vaccine prime the body to better fight liver tumors?
Disease control OngoingThis trial tests whether giving a personalized dendritic cell vaccine before a standard liver-directed therapy (TACE) can improve outcomes for people with advanced liver cancer that has not responded to other treatments. The vaccine is made from the patient's own immune cells and…
Phase 2 • Sponsor: Chang Gung Memorial Hospital • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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New drug combo shows promise for Hard-to-Treat cancers
Disease control OngoingThis study tests a new drug called E7386 combined with other cancer drugs in people with advanced solid tumors, including endometrial, liver, and colorectal cancers. The goal is to find the safest and most effective dose and to see if the combination can shrink tumors. About 300 …
Phase 1/2 • Sponsor: Eisai Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Sound waves zapping liver tumors? new device tested in 24 patients
Disease control OngoingThis trial tests a device called HistoSonics that uses focused ultrasound (sound waves) to mechanically destroy liver tumors without heat or needles. It includes 24 adults with liver cancer or tumors that spread to the liver. The main goals are to see if the device can fully cove…
Sponsor: HistoSonics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Sound waves zapping liver tumours without a scalpel
Disease control OngoingThis study tests a new, non-invasive treatment called histotripsy that uses high-intensity ultrasound waves to destroy liver tumours. It works by creating tiny bubbles in the tumour that burst and break it apart, while sparing healthy tissue. The trial will enroll 60 people with …
Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Sound waves zapping liver tumors: no knife needed?
Disease control OngoingThis trial tests a device called HistoSonics that uses focused ultrasound waves to mechanically destroy liver tumors without heat, needles, or incisions. About 47 adults with liver cancer or tumors that spread to the liver will receive this treatment. The main goals are to see if…
Sponsor: HistoSonics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New drug combo hopes to fight tough cancers in kids and young adults
Disease control OngoingThis study tests a combination of two drugs, cobolimab and dostarlimab, in children and young adults (up to age 21) with advanced solid tumors that have not responded to other treatments. The goal is to find the safest dose and see if the combination can shrink tumors. The study …
Phase 1/2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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AR goggles help doctors hit the mark in liver biopsies
Symptom relief By invitation onlyThis study tests a new augmented reality system called LUMENA that helps doctors guide needles during MRI scans of the liver. Twenty adults having a liver biopsy or tumor ablation will try the device. The goal is to see if it is safe and works well enough to use in most procedure…
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Sep 06, 2026 00:00 UTC
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New painkiller may replace opioids in liver cancer procedure
Symptom relief OngoingThis study tests esketamine, a drug related to ketamine, to control pain during a procedure that destroys liver tumors with heat. The goal is to find the right dose that works without needing opioids, which can cause breathing problems. 79 adults with liver cancer will receive es…
Phase 1/2 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Symptom relief
Last updated Jun 26, 2026 15:50 UTC
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Can smarter surgical tools cut liver surgery risks?
Knowledge-focused By invitation onlyThis study looks back at the records of about 800 adults who had minimally invasive liver surgery (laparoscopic, robotic, or hybrid) at specialized Italian centers. The goal is to see how the choice of surgical tools and techniques for cutting liver tissue relates to the risk of …
Sponsor: University of Molise • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Liver tumor treatment study halted before it began
Knowledge-focused CancelledThis study aimed to review past cases of a treatment called radioembolization (using tiny radiation beads) for liver tumors, including a rare type of bile duct cancer. The goal was to understand how well it works and what risks it carries. However, the study was withdrawn before …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Can new blood and imaging tests predict colon cancer liver spread?
Knowledge-focused OngoingThis pilot study aims to develop new ways to diagnose colon cancer and predict if it will spread to the liver. Researchers will collect blood and liver tissue samples from 51 patients undergoing surgery for colon cancer or benign colon growths. The goal is to find biomarkers that…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC