New painkiller may replace opioids in liver cancer procedure
NCT ID NCT07034950
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests esketamine, a drug related to ketamine, to control pain during a procedure that destroys liver tumors with heat. The goal is to find the right dose that works without needing opioids, which can cause breathing problems. 79 adults with liver cancer will receive esketamine during the procedure, and researchers will monitor their pain and breathing safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
esketamine
What this could lead to
If successful, this could provide a safer, opioid-free way to manage pain during liver tumor ablation, reducing breathing complications.
What could go wrong
This is an early-phase dose-finding study with only 79 participants. The results may not apply to all patients, and esketamine itself can cause side effects like dizziness or nausea.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Anesthesiology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Xiamen, China
Xiamen, Fujian, 361000, China