Limbal stem cell deficiency

This early-stage trial is testing an experimental eye drop called CSB-001 in 75 people with limbal stem cell deficiency, a condition where the eye's surface can't heal properly, leading to pain and vision loss. The study will check if the drops are safe and if they help improve s…

This study tests whether giving a laser treatment (transscleral cyclophotocoagulation) to lower eye pressure before a Boston keratoprosthesis (a plastic cornea implant) can prevent or slow glaucoma. Twenty adults who need the implant will receive one of two laser types 4-8 weeks …

This program provides access to BRM421 eye drops for adults with mild to moderate limbal stem cell deficiency (LSCD), a condition that can cause vision problems. Participants use the drops twice daily for at least 12 weeks and have monthly checkups. The goal is to see if this tre…

This study tests a new treatment for people who have lost vision in both eyes due to severe burns or rare eye diseases. Doctors take a small sample of cells from the inside of the patient's cheek, grow them into a thin sheet in the lab, and then transplant that sheet onto the dam…

This study watches 500 people with limbal stem cell deficiency (LSCD) to see how the disease changes over time. Researchers will track vision, eye comfort, and physical eye changes using questionnaires and tests. No new treatments are given—the goal is simply to learn more about …

This study aims to find biological markers (biomarkers) in blood, tears, and eye cells from 110 adults with seven rare eye diseases. Researchers will compare these markers between patients and healthy controls to see if they differ and if they relate to disease symptoms. The goal…

This long-term study collects data from over 100 eye clinics in Germany to see how corneal transplant surgeries have changed since 2001. Researchers track the number of surgeries, the types of procedures used, and the reasons people need them. The goal is to understand trends, no…

This study gathers eye scan images from 180 people with healthy eyes or eye diseases like glaucoma and retinal disease. The goal is to collect data using a new optical coherence tomography (OCT) device called A10900. No treatment or medication is given. The information will help …

This study is looking at 60 people with a genetic eye surface disease called limbal stem cell deficiency. Researchers want to find out if certain gene changes are linked to more severe disease. They will compare patients' genes with their eye health to look for patterns. This is …