Limbal stem cell deficiency
MONDO:002566725 clinical trials for this condition and its sub-types.
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Lab-grown stem cells may restore damaged eye surfaces
Disease control CompletedThis study tests whether a graft made from a patient's own or donor stem cells can repair the cornea's surface in people with limbal stem cell deficiency, a condition that causes pain, scarring, and vision loss. A small biopsy of limbal tissue is taken from a healthy eye or donor…
Phase: NA • Sponsor: Veerle Van Gerwen • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Eye membrane patch shows promise for blinding corneal disease
Disease control CompletedThis study tested whether a thin, clear membrane from the back of the cornea (Descemet's membrane) can help the eye heal in people with limbal stem cell deficiency, a condition that can cause blindness. Nineteen participants received the membrane as a patch on the eye's surface. …
Phase: PHASE1 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New registry aims to improve corneal transplants with AI
Knowledge-focused CompletedThis study created a nationwide registry to track long-term results of corneal surgeries and diseases. Researchers collected images and data from 19 participants to help understand what makes corneal transplants successful. The goal is to use this information to develop AI that c…
Sponsor: Nitin Vaswani • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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AI eye chatbot matches doctors in taking patient history
Knowledge-focused CompletedThis study tested whether a large language model (like ChatGPT) could collect medical history and suggest eye tests as well as doctors do. 172 patients with non-emergency eye problems took part. The AI's performance was compared to standard care, with senior specialists checking …
Phase: NA • Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC