Levator syndrome
MONDO:0023628Levator syndrome is characterized by sporadic pain in the rectum caused by spasm of a muscle near the anus (the levator ani muscle). The muscle spasm causes pain that typically is not related to defecation. The pain usually lasts less than 20 minutes. Pain may be brief and intense or a vague ache high in the rectum. It may occur spontaneously or with sitting and can waken a person from sleep. The pain may feel as if it would be relieved by the passage of gas or a bowel movement. In severe cases, the pain can persist for many hours and can recur frequently. A person may have undergone various unsuccessful rectal operations to relieve these symptoms.
Also known as: levator syndrome, painful spasm of anus, anorectal spasm, levator ani spasm syndrome, levator ani syndrome, paroxysmal proctalgia, proctalgia fugax, psychogenic anal spasm
9 clinical trials for this condition and its sub-types.
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New stapler aims to reduce leaks after colon surgery
Disease control Recruiting nowThis study is testing a new surgical stapler, called the Signia circular stapler, in people having left-sided colon, sigmoid, or rectal surgery. The goal is to see if it lowers the chance of a leak where the colon is reconnected. About 137 adults will take part, and the main focu…
Phase: NA • Sponsor: Medtronic - MITG • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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NIH launches massive GI data bank to fuel future discoveries
Knowledge-focused Recruiting nowThis study aims to collect medical data and biological samples (blood, urine, stool, and tissue) from up to 4,000 adults with known or suspected gastrointestinal diseases. Participants receive standard medical care at the NIH, and any extra samples or leftover tissue from procedu…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Fiber supplements may alter gut bacteria linked to colon cancer risk
Knowledge-focused Recruiting nowThis trial is testing whether taking daily fiber supplements can change the types and amounts of bacteria living in the colon. The study involves 120 adults with benign anal or colorectal conditions who are not currently on fiber supplements. Researchers will compare gut bacteria…
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC