Fiber supplements may alter gut bacteria linked to colon cancer risk
NCT ID NCT05643859
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial is testing whether taking daily fiber supplements can change the types and amounts of bacteria living in the colon. The study involves 120 adults with benign anal or colorectal conditions who are not currently on fiber supplements. Researchers will compare gut bacteria samples before and after fiber supplementation to see if the microbiome shifts in a way that might help prevent precancerous polyps.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dietary fiber supplement
- What this could lead to
- If successful, this study could point toward a simple dietary strategy to reduce colon polyp risk.
- What could go wrong
- This is an early observational study, not a treatment trial. It only measures microbiome changes, not actual polyp prevention, so results may not lead to direct health benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BENIGN COLORECTAL NEOPLASM are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
OHSU Knight Cancer Institute
RECRUITINGPortland, Oregon, 97239, United States