Fiber supplements may alter gut bacteria linked to colon cancer risk

NCT ID NCT05643859

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial is testing whether taking daily fiber supplements can change the types and amounts of bacteria living in the colon. The study involves 120 adults with benign anal or colorectal conditions who are not currently on fiber supplements. Researchers will compare gut bacteria samples before and after fiber supplementation to see if the microbiome shifts in a way that might help prevent precancerous polyps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dietary fiber supplement

What this could lead to

If successful, this study could point toward a simple dietary strategy to reduce colon polyp risk.

What could go wrong

This is an early observational study, not a treatment trial. It only measures microbiome changes, not actual polyp prevention, so results may not lead to direct health benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anus disorder benign neoplasm of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • OHSU Knight Cancer Institute

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact