Levator syndrome
MONDO:0023628Levator syndrome is characterized by sporadic pain in the rectum caused by spasm of a muscle near the anus (the levator ani muscle). The muscle spasm causes pain that typically is not related to defecation. The pain usually lasts less than 20 minutes. Pain may be brief and intense or a vague ache high in the rectum. It may occur spontaneously or with sitting and can waken a person from sleep. The pain may feel as if it would be relieved by the passage of gas or a bowel movement. In severe cases, the pain can persist for many hours and can recur frequently. A person may have undergone various unsuccessful rectal operations to relieve these symptoms.
Also known as: levator syndrome, painful spasm of anus, anorectal spasm, levator ani spasm syndrome, levator ani syndrome, paroxysmal proctalgia, proctalgia fugax, psychogenic anal spasm
9 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Pain management study pulled before it even started
Knowledge-focused TerminatedThis study aimed to see if a team of doctors, nurses, and pharmacists working together could help people recover better after anorectal surgery. It planned to compare standard care with this team-based approach in 126 adults. However, the study was withdrawn before any participan…
Phase: NA • Sponsor: China-Japan Friendship Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC