Legg-Calve-Perthes disease

MONDO:0007885

A hip region disease that is characterized by uni- or bilateral avascular necrosis (AVN) of the femoral head in children. In a small percentage of cases, mutations in the COL2A1 gene were found to be responsible.

Also known as: Legg Calvé Perthes Disease, Legg-CALVE-Perthes disease, Legg-Calve-Perthes disease, Legg-Calve-Perthes symptom, Legg-Calve-Perthes syndrome, Legg-Calvé-Perthes disease, Legg-Perthes disease, Osteochondrosis of the capital femoral epiphysis

54 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Musculoskeletal system disorder (196) Hereditary disease (172) Connective tissue disorder (67) Osteonecrosis (56) Bone disorder (47) Syndromic disease (24) Human disease (14) Osteochondrosis (8) Skeletal system disorder (4)

Trials to join now! 24 Not yet recruiting 7 Not yet finished but already full! 8 Completed 14 Terminated 1

Scientists gather leftover surgical tissue to unlock secrets of bone disease

Knowledge-focused Terminated

This study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …

Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused

Last updated Jun 27, 2026 07:52 UTC

Legg-Calve-Perthes disease

Broader categories

Scientists gather leftover surgical tissue to unlock secrets of bone disease