LCAT deficiency
MONDO:0018999LCAT (lecithin-cholesterol acyltransferase) deficiency is a rare lipoprotein metabolism disorder characterized clinically by corneal opacities, and sometimes renal failure and hemolytic anemia, and biochemically by severely reduced HDL cholesterol.
Also known as: lecithin-cholesterol acyltransferase deficiency
14 clinical trials for this condition and its sub-types.
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Broader categories
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One patient gets experimental enzyme to fight rare kidney disease
Disease control CompletedThis study tested an artificial version of the LCAT enzyme (ACP-501) in one person with familial LCAT deficiency, a rare genetic condition that leads to low 'good' cholesterol and kidney failure. The participant received several infusions of the drug over weeks, with regular bloo…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Could a 5:2 diet melt fat from your liver?
Disease control CompletedThis study looked at whether an 8-week 5:2 intermittent fasting diet could help people with fatty liver disease. Eighty adults with excess liver fat followed the diet, eating normally for 5 days and restricting calories to 500 kcal on 2 non-consecutive days each week. Researchers…
Phase: NA • Sponsor: Beijing Chao Yang Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Study reveals HPV vaccine gaps in teens with chronic illness
Knowledge-focused CompletedThis study looked at how many girls and young women aged 11 to 20 with chronic diseases (like diabetes or immune conditions) got the HPV vaccine, compared to those without chronic illness. Researchers reviewed records of 223 participants from a hospital in France. The goal was to…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC