Could a 5:2 diet melt fat from your liver?

NCT ID NCT04795973

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether an 8-week 5:2 intermittent fasting diet could help people with fatty liver disease. Eighty adults with excess liver fat followed the diet, eating normally for 5 days and restricting calories to 500 kcal on 2 non-consecutive days each week. Researchers measured changes in liver fat, body weight, and metabolic health markers before and after the diet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

5:2 intermittent fasting diet

What this could lead to

If successful, this diet approach could offer a simple, drug-free way to reduce liver fat and improve metabolic health in people with fatty liver disease.

What could go wrong

This is a small, completed study without a control group, so results may not be definitive. The diet requires strict adherence and may not work for everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fatty liver disease Insulin Resistance metabolic disease metabolic dysfunction-associated steatotic liver disease Norum disease thyroid hormone resistance syndrome Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Chao-yang Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100020, China