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LCAT deficiency

MONDO:0018999

LCAT (lecithin-cholesterol acyltransferase) deficiency is a rare lipoprotein metabolism disorder characterized clinically by corneal opacities, and sometimes renal failure and hemolytic anemia, and biochemically by severely reduced HDL cholesterol.

Also known as: lecithin-cholesterol acyltransferase deficiency

4 clinical trials for this condition and its sub-types.

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Sub-types

Norum disease (2) Fish eye disease (1)

Broader categories

Disease (717) Metabolic disease (241) Human disease (15) Hypoalphalipoproteinemia (1) Disease by developmental or physiological process (0)
Trials to join now! 1 Not yet recruiting 1 Completed 2
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  • Will breakfast change how this diabetes drug works?

    Knowledge-focused Not yet recruiting

    This early-stage trial in 28 healthy adults tests whether eating a meal changes how the body absorbs a single tablet containing three diabetes medicines (gemigliptin, dapagliflozin, and metformin). Participants take the pill once while fasting and once after a meal, and researche…

    Phase 1 • Sponsor: LG Chem • Aim: Knowledge-focused

    Last updated Jun 27, 2026 12:06 UTC

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