Kluver-Bucy syndrome
MONDO:0005817Kluver Bucy syndrome is a rare behavioral impairment characterized by inappropriate sexual behaviors and mouthing of objects. Other signs and symptoms include diminished ability to visually recognize objects,loss of normal fear and anger responses, memory loss, distractibility, seizures, and dementia. It is associated with damage to the anterior temporal lobes of the brain. Cases have been reported in association with herpes encephalitis and head trauma. Treatment is symptomatic and may include the use of psychotropic medications.
Also known as: KLüver-Bucy syndrome, KLuever-Bucy syndrome, Kluver Bucy syndrome, bilateral temporal lobe disorder, memory loss, extreme sexual behavior, placidity, and visual distractibility, post-encephalitic Kluver Bucy syndrome (type), post-traumatic Kluver Bucy syndrome (type), syndrome, Kluver-Bucy
85 clinical trials for this condition and its sub-types.
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New community program targets COPD and mental health together
Disease control CompletedThis completed trial in Xishui, China, tested a community-based program for 3,571 adults aged 35 and older who were at high risk for COPD and had mental health symptoms. The program included lung function tests, digital mental health support, smoking cessation help, and health ed…
Phase: NA • Sponsor: Peking Union Medical College • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Molecular map may guide treatment for mysterious inflammatory illnesses
Disease control CompletedThis study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Rural patients get Hospital-Level care at home in landmark trial
Disease control CompletedThis study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Mediterranean diet shows promise for metabolic health in psychiatric patients
Disease control CompletedThis completed study tested whether a Mediterranean diet could improve metabolic syndrome markers in 30 hospitalized adults with psychiatric conditions. Participants followed either a Mediterranean diet or a standard hospital diet for 8 weeks, then switched. Researchers measured …
Phase: NA • Sponsor: King Saud University • Aim: Disease control
Last updated Jun 26, 2026 15:01 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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One-Hour brain infection test could save lives
Diagnosis CompletedThis study tested a new rapid diagnostic panel called QIAstat-Dx that can detect 15 different bacteria, viruses, and fungi causing meningitis and encephalitis in just one hour. Researchers compared its accuracy against standard lab tests using 170 stored spinal fluid samples. If …
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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New PET tracer aims to light up hidden infections
Diagnosis CompletedThis early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New PET scan technique aims to sniff out hidden infections
Diagnosis CompletedThis early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Video game therapy shows promise for mental health
Symptom relief CompletedThis study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…
Phase: NA • Sponsor: University of Salamanca • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Study explores how family and friends impact caregiver health
Knowledge-focused CompletedThis completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Can peers help others recover? small study tests new program
Knowledge-focused CompletedThis study tested whether a 10-week recovery program, co-led by a peer with mental illness and a professional, is feasible for people with mental illness in Taiwan. Twenty participants completed the program, which focused on recovery concepts, strengths, and goal setting. Researc…
Phase: NA • Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Brain scans and thinking tests aim to unlock secrets of Self-Harm
Knowledge-focused CompletedThis study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Peer support after psychiatric stay shows promise in small VA study
Knowledge-focused CompletedThis study tested a program called Recovery Bridge, where trained peer specialists (people with lived experience of mental illness) helped veterans leaving a psychiatric hospital connect to outpatient care and community life. Fifteen veterans took part to see if the program was f…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Sleep struggles widespread in psychiatric wards
Knowledge-focused CompletedThis study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Can doing meaningful activities boost recovery in mental illness? new study says maybe.
Knowledge-focused CompletedThis study tested an 8-month program called 'Meaningful Activities and Recovery' (MA&R) for people with mental illness. The program helps people take part in activities that matter to them. 139 adults took part to see if the program improves activity engagement, recovery, and qua…
Phase: NA • Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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MRI contrast dye may skew brain scans, study finds
Knowledge-focused CompletedThis study looked at how gadolinium, a dye used in MRI scans, changes the QSM signal in the brain's white matter. 73 patients with inflammatory central nervous system conditions had MRI scans before and after receiving gadolinium. The goal was to measure any differences in the si…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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ICU antibiotic dosing: what really matters?
Knowledge-focused CompletedThis study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Hidden ADHD: study reveals how many adults are undiagnosed
Knowledge-focused CompletedThis completed study looked at 224 adults who already had at least one psychiatric condition to see how many also had undiagnosed ADHD. Researchers measured how often ADHD was missed and tracked quality of life in those diagnosed. The goal is to highlight the need for better dete…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC