Intrinsic asthma
MONDO:0004765An asthma that is triggered by factors not related to allergies such as anxiety, stress, exercise, cold air, dry air, hyperventilation, smoke, viruses, chemical irritants, autonomic imbalance, hormonal deficiencies and psychogenic influences. It is characterized by airway obstruction and inflammation that is at least partially reversible with medication. The symptoms include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness.
Also known as: non-allergic asthma
17 clinical trials for this condition and its sub-types.
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Broader categories
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Can a new drug help people with aspirin allergy, asthma, and nasal polyps?
Disease control OngoingThis Phase 2 trial is testing dupilumab (Dupixent) in 17 people with aspirin-exacerbated respiratory disease (AERD), a condition that includes asthma, nasal polyps, and severe reactions to aspirin. The study aims to see if the drug can reduce markers of inflammation and improve s…
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 26, 2026 18:12 UTC
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Vitamin D3 may tame asthma in overweight teens
Disease control OngoingThis study tests whether vitamin D3 supplements can improve asthma control in adolescents aged 12-17 who have obesity, non-allergic asthma, and vitamin D deficiency. Participants receive either a high or standard daily dose of vitamin D3 for three months. Researchers will measure…
Phase: NA • Sponsor: Hospital Infantil de Mexico Federico Gomez • Aim: Disease control
Last updated Jun 26, 2026 17:20 UTC
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Cleveland clinic launches asthma research to develop better tests and treatments
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to improve how asthma is diagnosed and treated by developing new tests and targeted therapies. Researchers will enroll 60 adults with asthma to test a special oil additive and measure lung function and quality of life. The goal is to create better tools for managi…
Phase: EARLY_PHASE1 • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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New breath test could replace painful lung scopes
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to see if a simple, non-invasive breathing test can accurately measure the acidity (pH) in the airways, which is often abnormal in lung diseases. Researchers will compare results from this breath test with standard methods in 150 healthy volunteers and people with…
Phase: PHASE2 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC