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Immunodeficiency 19

MONDO:0014280

Any severe combined immunodeficiency in which the cause of the disease is a mutation in the CD3D gene.

Also known as: CD3D severe combined immunodeficiency (disease), CD3delta deficiency, immunodeficiency 19, immunodeficiency type 19, severe combined immunodeficiency (disease) caused by mutation in CD3D, CD3-Delta deficiency, IMD19, SCID, T cell-negative, B cell-positive, NK cell-positive

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Hereditary disease (188) Immune system disorder (150) Immunodeficiency disease (55) Severe combined immunodeficiency (23) Human disease (15) Combined immunodeficiency (3) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0)
Completed 1 Terminated 1
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  • Bubble baby breakthrough? experimental cell shot aims to reboot immune system faster

    Disease control Completed

    This early-phase trial tested whether injecting special immune-building cells (HTLPs) could help children with severe combined immunodeficiency (SCID) rebuild their immune system faster after a partially matched stem cell transplant. Only 4 children took part. The goal was to see…

    Phase 1/2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control

    Last updated Jun 27, 2026 12:36 UTC

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