Hypogonadotropic hypogonadism
MONDO:0018555Abnormal ovarian or testicular function due to insufficient hormonal stimulation from the hypothalamic-pituitary axis.
Also known as: Normosmic idiopathic hypogonadotropic hypogonadism, central hypogonadism, gonadotropic deficiency, hypogonadism, hypogonadotropic, hypogonadotropic hypogonadism, hypogonadotropic hypogonadism with or without anosmia, low gonadotropins (secondary hypogonadism), nIHH
95 clinical trials for this condition and its sub-types.
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Broader categories
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Daily pill may replace growth hormone shots for children
Disease control Not yet recruitingThis study evaluates the long-term safety of an oral medication called LUM-201 for children with growth hormone deficiency (GHD). Children who completed a prior 12-month trial can receive LUM-201 daily for up to 36 additional months. The goal is to see if the pill is safe and tol…
Phase: PHASE3 • Sponsor: Lumos Pharma • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Can a simple muscle exercise improve erectile function in men with low testosterone?
Disease control Not yet recruitingThis study tests whether pelvic floor muscle training (PFMT) with a handheld biofeedback device can improve erectile function and sexual quality of life in men with functional hypogonadism (low testosterone) and erectile dysfunction. Participants are randomly assigned to PFMT wit…
Phase: NA • Sponsor: Poznan University of Physical Education • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New Long-Acting growth hormone shot could mean fewer needles for kids
Disease control Not yet recruitingThis study tests a new medicine called GenSci134, a long-acting growth hormone, in 128 children with growth hormone deficiency (GHD). The goal is to find the best dose and see if it is safe and helps children grow taller. In the first part, children get one shot of GenSci134; in …
Phase: PHASE1, PHASE2 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Could a drink replace daily shots for growth hormone deficiency?
Disease control Not yet recruitingThis study tests an oral medicine called GS3-007a for children with growth hormone deficiency. In the first part, kids receive different doses or a placebo for 14 days to check safety. In the second part, they take the chosen dose or a standard injection for 52 weeks to see how w…
Phase: PHASE1, PHASE2 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Can a natural supplement boost testosterone and improve sex life in aging men?
Symptom relief Not yet recruitingThis study looks at whether a natural supplement called D-Chiro-inositol can help men aged 50 to 75 who have low testosterone (functional hypogonadism) and related sexual issues. Over 3 months, 35 men will take the supplement to see if their hormone levels and sexual function imp…
Phase: NA • Sponsor: Cardarelli Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New hope for Prader-Willi: drug targets uncontrollable hunger
Symptom relief Not yet recruitingThis study tests an experimental drug called BMB-101 in 16 adults with Prader-Willi syndrome who struggle with severe, constant hunger. The trial is double-blind and placebo-controlled, meaning some participants get the drug and some get a dummy treatment, and neither they nor th…
Phase: PHASE2 • Sponsor: Bright Minds Biosciences Pty Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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300 belgian kids to help unlock growth Hormone's metabolic secrets
Knowledge-focused Not yet recruitingThis study will follow 300 Belgian children with growth hormone deficiency for three years to see how their bodies respond to daily or weekly growth hormone shots. Researchers will measure growth, weight, blood sugar, fats, and other health markers. The goal is to understand whic…
Phase: NA • Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Testicle blood flow may predict fertility surgery success
Knowledge-focused Not yet recruitingThis study looks at 40 infertile men with varicoceles (enlarged veins in the scrotum) to see if blood flow measurements in the testicles can predict how well they will respond to surgery. Participants will have ultrasound and blood tests before and three months after a standard m…
Phase: NA • Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC