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Hypogonadotropic hypogonadism
MONDO:0018555Abnormal ovarian or testicular function due to insufficient hormonal stimulation from the hypothalamic-pituitary axis.
Also known as: Normosmic idiopathic hypogonadotropic hypogonadism, central hypogonadism, gonadotropic deficiency, hypogonadism, hypogonadotropic, hypogonadotropic hypogonadism, hypogonadotropic hypogonadism with or without anosmia, low gonadotropins (secondary hypogonadism), nIHH
100 clinical trials for this condition and its sub-types, 19 tagged with Hypogonadotropic hypogonadism itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hypogonadotropic hypogonadism
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Congenital hypogonadotropic hypogonadism 0 trials · 83 incl. sub-types
25 sub-types
- Combined pituitary hormone deficiencies, genetic form 1 trial · 42 incl. sub-types Sub-types →
- Prader-Willi syndrome 32 trials Sub-types →
- CHARGE syndrome 4 trials Sub-types →
- Hypogonadotropic hypogonadism 7 with or without anosmia 3 trials
- Arhinia, choanal atresia, and microphthalmia 1 trial
- Isolated congenital hypogonadotropic hypogonadism 0 trials · 1 incl. sub-types Sub-types →
- Obesity due to congenital leptin deficiency 1 trial
- Obesity due to leptin receptor gene deficiency 1 trial
- Obesity due to prohormone convertase I deficiency 1 trial
- ANE syndrome 0 trials
- Kallmann syndrome-heart disease syndrome 0 trials
- Laurence-Moon syndrome 0 trials
- Martsolf syndrome 1 0 trials
- Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome 0 trials
- Prader-Willi-like syndrome 0 trials Sub-types →
- Woodhouse-Sakati syndrome 0 trials
- X-linked adrenal hypoplasia congenita 0 trials Sub-types →
- Ataxia-hypogonadism-choroidal dystrophy syndrome 0 trials
- Brachytelephalangy-dysmorphism-Kallmann syndrome 0 trials
- Cerebellar ataxia-hypogonadism syndrome 0 trials Sub-types →
- Familial adrenal hypoplasia with absent pituitary luteinizing hormone 0 trials
- Hypogonadotropic hypogonadism-frontoparietal alopecia syndrome 0 trials
- Hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 0 trials
- Hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome 0 trials
- Polyendocrine-polyneuropathy syndrome 0 trials
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Kallmann syndrome 3 trials
18 sub-types
- Hypogonadotropic hypogonadism 1 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 11 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 14 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 15 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 16 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 17 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 18 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 19 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 2 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 20 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 21 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 22 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 3 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 4 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 5 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 6 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 8 with or without anosmia 0 trials
- Hypogonadotropic hypogonadism 9 with or without anosmia 0 trials
Most studied deeper sub-types
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AI-Crafted supplement aims to restore testosterone naturally
Disease control By invitation onlyThis trial tests whether a daily nutritional supplement, designed with artificial intelligence to target gut bacteria, can increase testosterone production in men aged 30-65 with functional secondary hypogonadism—a condition where the body doesn't make enough testosterone despite…
Sponsor: Varol TUNALI • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Can acne drug or hormone shots help men with low sperm count?
Disease control By invitation onlyThis study tests two treatments—isotretinoin (an acne medication) and hCG (a hormone)—to see if they can help men with low or no sperm count produce moving sperm. About 100 men aged 19 to 50 will take one of the drugs for three months. The goal is to find new options for male inf…
Phase 2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Jun 27, 2026 12:10 UTC
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Scientists probe link between obesity and infertility
Knowledge-focused OngoingThis study investigates how obesity-related factors like high insulin and fat levels may disrupt fertility in women. Researchers will measure hormone changes and metabolic responses in 84 women. The goal is to understand the underlying causes and inform future treatments to impro…
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC