Hypertensive heart disease
MONDO:0001302Abnormal enlargement of the heart resulting from long-standing hypertension.
Also known as: hypertensive heart disease, hypertensive cardiomegaly, hypertensive cardiopathy, hypertensive cardiovascular disease
7 clinical trials for this condition and its sub-types.
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Could a natural compound in food help aging hearts?
Disease control CompletedThis study tests whether spermidine, a natural substance found in foods like soy and aged cheese, can improve heart and muscle health in elderly people with coronary artery disease. 180 participants aged 65 and older will receive either spermidine capsules or a placebo for a peri…
Phase 2 • Sponsor: University of Aarhus • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Heart surgery showdown: which fix best unblocks the heart?
Disease control CompletedThis study looked at 100 people with hypertrophic cardiomyopathy, a condition where the heart muscle thickens and blocks blood flow. Researchers compared different surgical techniques—removing part of the thickened heart muscle alone or combined with repairing the mitral valve—to…
Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Drug combo may better tame high blood Pressure's heart damage
Disease control CompletedThis completed study tested whether combining valsartan and hydrochlorothiazide works better than valsartan alone for people with hypertensive heart disease. 118 adults aged 18-70 took part over 8 weeks. Researchers measured blood pressure, heart changes on ECG, and symptoms to s…
Phase 1 • Sponsor: Shaikh Zayed Hospital, Lahore • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC