Heart surgery showdown: which fix best unblocks the heart?

NCT ID NCT03877731

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 100 people with hypertrophic cardiomyopathy, a condition where the heart muscle thickens and blocks blood flow. Researchers compared different surgical techniques—removing part of the thickened heart muscle alone or combined with repairing the mitral valve—to see which best relieves symptoms and keeps patients out of the hospital. The goal is to find the most effective surgery for this heart problem.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgery (septal myectomy with or without mitral valve repair)

What this could lead to

If successful, this could identify the best surgical approach to relieve heart blockage and improve survival without hospital readmission for people with hypertrophic cardiomyopathy.

What could go wrong

This is a completed observational study with 100 participants, not a large randomized trial. Results may not apply to all patients, and surgery carries risks like infection or heart complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertensive heart disease hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cardiology research institute, National Research Medical Center of the Russian Academy of Sciences

    Tomsk, 634012, Russia