Hookworm infectious disease

This study tested a new vaccine to prevent hookworm infection in 39 healthy adults who had never had hookworms before. Participants received different versions of the vaccine and were then exposed to hookworms in a controlled setting to see if the vaccine could prevent infection.…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This study tested whether higher doses of ivermectin, combined with albendazole, are safe and effective for treating whipworm infections in children aged 2 to 5 years. The trial involved 260 children in Tanzania and compared different doses of ivermectin, including a new dissolva…

This study tested whether combining two drugs—moxidectin and albendazole—works better than albendazole alone for treating whipworm infections in children aged 6 to 12. The trial took place in Tanzania and involved 224 children. Researchers measured how many children were cured an…

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …