Heritable pulmonary arterial hypertension
MONDO:0017148Heritable pulmonary arterial hypertension (HPAH) is a form of pulmonary arterial hypertension (PAH), occurring due to mutations in PAH predisposing genes or in a familial context. HPAH is characterized by elevated pulmonary arterial resistance leading to right heart failure. HPAH is progressive and potentially fatal.
Also known as: FPAH, HPAH, HpaH, familial pulmonary arterial hypertension, hereditary pulmonary arterial hypertension
31 clinical trials for this condition and its sub-types.
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New hope for PAH patients: Long-Term drug safety trial opens
Disease control ENROLLING_BY_INVITATIONThis study looks at the long-term safety of the drug ralinepag in people with pulmonary arterial hypertension (PAH), a serious lung condition that makes it hard to breathe. About 1,000 adults who were in earlier ralinepag studies can join. The goal is to see if the drug remains s…
Phase: PHASE3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Massive study aims to redefine Lung-Heart disease
Knowledge-focused OngoingThis study looks at nearly 1,200 people with or at risk for pulmonary hypertension (high blood pressure in the lungs). Researchers use many advanced tests to find new ways to classify the disease and identify biomarkers. The goal is to better understand the disease and improve fu…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC