Hallermann-Streiff syndrome

MONDO:0009318

Hallermann-Streiff syndrome is a rare genetic syndrome characterized mainly by head and facial abnormalities such as bird-like facies (with beak-shaped nose and retrognathia), hypoplastic mandible, brachycephaly with frontal bossing, dental abnormalities (e.g. absence of teeth, natal teeth, supernumerary teeth, severe agenesis of permanent teeth, enamel hypoplasia) hypotrichosis, various ophthalmic disorders (e.g. congenital cataracts, bilateral microphthalmia, ptosis, nystagmus) and atrophy of skin (especially around the center of face and nose) as well as telangiectasia and proportionate short stature. Intellectual disability is reported in some cases.

Also known as: FranC'ois dyscephalic syndrome, Francois dyscephalic syndrome, François dyscephalic syndrome, Hallermann syndrome, Hallermann's syndrome, Hallermann-Streiff syndrome, oculomandibulofacial syndrome, HSS

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