Exfoliation syndrome
MONDO:0008327An autosomal dominant disorder caused by mutations in the LOXL1 gene, encoding lysyl oxidase homolog 1. The condition is characterized by abnormal fibrillar extracellular material in anterior segment tissues, and may lead to glaucoma.
Also known as: XFG, XFS, pseudoexfoliation glaucoma
40 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New eye implant could reduce glaucoma drops
Disease control CompletedThis study tested a small implant called Supraflow v2.2 in 57 adults with open-angle or narrow-angle glaucoma. The implant is placed inside the eye to help drain fluid and lower eye pressure. The goal was to see if it safely reduces pressure and the need for daily eye drops over …
Phase: NA • Sponsor: Ciliatech • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New 'Micro' eye surgery could ease glaucoma treatment
Disease control CompletedThis study tested a new, less invasive surgery called MIMS for people with glaucoma. The goal was to see if it lowers eye pressure as well as traditional surgery but with fewer side effects. 23 adults with glaucoma took part. The results will help doctors understand if MIMS is a …
Phase: NA • Sponsor: Hôpital Privé de la Baie • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Eye flakes and wrist pain: surprising connection found?
Knowledge-focused CompletedThis study examined whether pseudoexfoliation syndrome (an eye condition) is related to carpal tunnel syndrome (a wrist nerve problem). Researchers measured blood markers in 159 adults aged 50-80. The goal was to see if these conditions share a common cause, not to test a treatme…
Sponsor: Ankara Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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App aims to clear up glaucoma drop confusion
Knowledge-focused CompletedThis study tested whether a simple app, available in English, Spanish, and Cantonese, could help glaucoma patients better remember their multiple eye drop schedules. Twenty participants either used the app or received standard instructions. After one month, researchers compared h…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC