Encephalitis lethargica
MONDO:0019384A form of encephalitis, the etiology of which is uncertain, that is characterized by lethargy and headache.
Also known as: Von Economo encephalitis, encephalitis lethargica, epidemic encephalitis, lethargic encephalitis, von Economo's disease, Von Economo’s disease
20 clinical trials for this condition and its sub-types.
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Could immune checkpoint drugs tame a deadly brain virus?
Disease control Recruiting nowThis study is testing whether immune checkpoint inhibitors, drugs that help the immune system fight infections, can improve outcomes for people with progressive multifocal leukoencephalopathy (PML), a rare brain virus. Researchers will follow 66 patients over a year, measuring di…
Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Can donor cells stop viruses after transplant?
Disease control Recruiting nowThis study tests whether giving patients donor-derived immune cells (VSTs) on a regular schedule can prevent dangerous viral infections after a stem cell transplant. 180 participants will be randomly assigned to receive VSTs either on a fixed schedule or only when a virus is dete…
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Supercharged donor cells take on viruses after transplant
Disease control Recruiting nowThis study tests whether specially grown donor immune cells (viral-specific T-cells) can safely treat viral infections that often occur after a stem cell transplant. These infections can be serious and sometimes don't respond to standard antiviral drugs. The approach aims to boos…
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Smart sensors could spot Parkinson's earlier and more accurately
Diagnosis Recruiting nowThis study aims to develop computer models that can help diagnose and monitor Parkinson's disease by analyzing eye movements and walking patterns. Researchers will collect data from 100 people with Parkinson's or similar conditions using special devices. The goal is to make diagn…
Sponsor: machineMD AG • Aim: Diagnosis
Last updated Jun 27, 2026 07:53 UTC
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Scientists launch major study to track viruses in healthy and immunocompromised patients
Knowledge-focused Recruiting nowThis study aims to collect samples and medical information from people of all ages who have or have been exposed to viral infections, including COVID-19 and herpes. Researchers want to understand how viruses affect healthy individuals versus those with weakened immune systems. Pa…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Massive Parkinson's registry launches in china to track 100,000 patients
Knowledge-focused Recruiting nowThis study aims to collect health information from 100,000 people with Parkinsonian disorders in China over 10 years. Participants use an online platform to report symptoms, quality of life, and other health details every 3 months. The goal is to better understand how the disease…
Sponsor: Huashan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC