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Eisenmenger syndrome

MONDO:0019944

Eisenmenger syndrome (ES) is an form of pulmonary arterial hypertension (PAH) associated with unoperated congenital heart disease and is characterized by congenital heart malformations with reversed or bi-directional shunting through an intra-cardiac or intervascular (usually aorto-pulmonary) communication with the development of PAH.

Also known as: Eisenmenger's syndrome

24 clinical trials for this condition and its sub-types.

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Broader categories

Hypertensive disorder (1192) Cardiovascular disorder (1051) Disease (680) Pulmonary hypertension (216) Pulmonary arterial hypertension (184) Vascular disorder (135) Syndromic disease (25) Human disease (14) Arterial disorder (11) Disease by body system or component (0)

Trials to join now! 13 Not yet recruiting 6 Not yet finished but already full! 1 Completed 4

Massive study aims to redefine Lung-Heart disease

Knowledge-focused Ongoing

This study looks at nearly 1,200 people with or at risk for pulmonary hypertension (high blood pressure in the lungs). Researchers use many advanced tests to find new ways to classify the disease and identify biomarkers. The goal is to better understand the disease and improve fu…

Sponsor: The Cleveland Clinic • Aim: Knowledge-focused

Last updated Jun 27, 2026 07:57 UTC