Dystonia 12
MONDO:0007496Rapid-onset dystonia-parkinsonism (RDP) is a very rare movement disorder, characterized by the abrupt onset of parkinsonism and dystonia, often triggered by physical or psychological stress.
Also known as: ATP1A3 dystonic disorder, DYT-ATP1A3, DYT12, dystonia 12, dystonia type 12, dystonia-12, dystonic disorder caused by mutation in ATP1A3, RDP
26 clinical trials for this condition and its sub-types.
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Can a One-Time bone drug shield Parkinson's patients from fractures?
Prevention CompletedThis study tested whether a single infusion of zoledronic acid (Reclast) can prevent fractures in men and women aged 60 and older with Parkinson's disease or related conditions. Over 2,700 participants were randomly assigned to receive either the drug or a placebo, and were follo…
Phase: PHASE4 • Sponsor: California Pacific Medical Center Research Institute • Aim: Prevention
Last updated Jun 27, 2026 14:01 UTC
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Bubble therapy shows promise for Parkinson's symptoms
Symptom relief CompletedThis study tested whether infusing tiny bubbles of oxyhydrogen gas could help people with Parkinsonism. 35 adults received the infusion alongside their usual care. Researchers measured changes in disease severity, thinking ability, and quality of life. The goal was to see if this…
Phase: PHASE2, PHASE3 • Sponsor: dr. Siti Nurlaela, SpN • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Brain study sheds light on Parkinson's and tics
Knowledge-focused CompletedThis completed study from the National Institute of Neurological Disorders and Stroke aimed to better understand how the brain controls movement and what goes wrong in movement disorders like Parkinson's disease, Tourette's syndrome, and dystonia. Over 1,200 adults—both patients …
Phase: NA • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Dystonia study reveals hidden brain changes beyond muscle twists
Knowledge-focused CompletedThis study looked at 102 adults with dystonia, a condition causing involuntary muscle contractions. Researchers used questionnaires and brain wave recordings to assess memory, attention, mood, and decision-making. The goal was to better understand the non-motor symptoms of dyston…
Phase: NA • Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Parkinson's Patients' hospital stays under the microscope
Knowledge-focused CompletedThis completed study looked at over 2,500 people with Parkinson's disease who were admitted to the hospital through the emergency room. Researchers wanted to find the main reasons for these hospital stays and compare them to people of the same age without Parkinson's. The goal wa…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Wrist-Worn gadget could help doctors monitor Parkinson's at home
Knowledge-focused CompletedThis study tested a wrist-worn device called the Personal KinetiGraph (PKG) to see if it can accurately measure movement problems in people with Parkinson's disease. Nineteen participants wore the device while researchers compared its readings to standard clinical tests and video…
Sponsor: Global Kinetics Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC