Dental fluorosis
MONDO:0006722A condition that results from excessive fluoride ingestion during tooth development, resulting in tooth discoloration ranging from white streaks to brown stains and cracks or pits in the tooth enamel.
Also known as: fluorosis, mottled teeth, mottling of enamel
12 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Can a special varnish erase white spots left by braces?
Disease control CompletedThis study tests two types of fluoride varnish—one that hardens with a special light and a standard one—to see if they can reverse white spot lesions (early cavities) that often appear after braces are removed. About 38 teenagers who are finishing orthodontic treatment will recei…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Could a 3D camera replace the Dentist's mirror for kids?
Diagnosis CompletedThis study tested whether a 3D intraoral scanner can detect cavities, tooth wear, and fluorosis in children's baby teeth as accurately as a traditional visual exam. Thirty-six children aged 3 to 12 had their teeth cleaned, then examined both visually and with a 3D scan during a s…
Phase: NA • Sponsor: Indiana University • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Battle of the smile fixers: which treatment brightens Fluorosis-Stained teeth best?
Symptom relief CompletedThis trial compares two minimally invasive treatments—Antivet and Opalustre—for improving the appearance of mild enamel fluorosis, a condition that causes tooth discoloration. Adults aged 20 to 35 with mild fluorosis on their front teeth are randomly assigned to receive one of th…
Phase: NA • Sponsor: October University for Modern Sciences and Arts • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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New study tests simple ways to erase chalky white spots on teeth without drilling
Symptom relief CompletedDental fluorosis can leave chalky white spots on front teeth, affecting appearance even when the enamel is intact. This trial compares two gentle treatments—resin infiltration and enamel microabrasion followed by a calcium-phosphate paste—for masking those spots. Researchers meas…
Phase: NA • Sponsor: Hue University of Medicine and Pharmacy • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC