Croup
MONDO:0005722Acute upper respiratory airways infection that results in the swelling of the larynx. It is usually caused by parainfluenza viruses. Signs include a characteristic barking cough and stridor.
Also known as: acute laryngotracheobronchitis, acute obstructive laryngitis, acute laryngotracheitis
50 clinical trials for this condition and its sub-types.
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Could a nasal spray vaccine stop croup in kids?
⭐️ VACCINE ⭐️ TerminatedThis study tests an experimental nasal vaccine made from a harmless virus (Sendai virus) that is similar to the one causing croup. The goal is to see if it is safe and helps children ages 1 to 5 build protection against croup. About 54 children will receive the vaccine as nose dr…
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:02 UTC
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New rapid test could slash unnecessary antibiotic use in emergency rooms
Diagnosis OngoingThis study tests a fast point-of-care PCR test (Spotfire) that quickly identifies whether a respiratory infection is caused by a virus. The goal is to give ER doctors results faster so they can avoid prescribing antibiotics when they won't help. The trial enrolls 200 adults with …
Phase: NA • Sponsor: Christopher Payette • Aim: Diagnosis
Last updated Jun 27, 2026 07:58 UTC
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Scientists sniff out virus spread with home air monitors
Knowledge-focused TerminatedThis study looks at whether air samplers placed in homes can detect viruses that cause colds and flu, and how that compares to standard nasal swabs. About 422 students and their families will participate. The goal is to better understand how respiratory viruses spread through hou…
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Could a simple spit test replace the dreaded deep nose swab?
Knowledge-focused OngoingThis study compares new, less invasive ways to collect samples for respiratory virus testing—like a nasal wash or saliva—against the standard deep nose swab. Researchers want to see if these gentler methods work just as well and cause less pain. About 1,000 adults in the emergenc…
Phase: NA • Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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15-Minute nasal swab could curb antibiotic overuse for colds
Knowledge-focused ENROLLING_BY_INVITATIONThis study places a rapid testing device in primary care clinics to help doctors quickly identify whether a cold-like illness is caused by a virus or bacteria. About 8,000 adults with symptoms like cough or runny nose will get a nasal swab, with results in 15 minutes. The goal is…
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC