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Craniodiaphyseal dysplasia

MONDO:0009031

Craniodiaphyseal dysplasia is a rare sclerotic bone disorder with a variable phenotypic expression with massive generalized hyperostosis and sclerosis, particularly of the skull and facial bones, that may lead to severe deformity.

Also known as: Lionitis, craniodiaphyseal dysplasia, CDD

35 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Musculoskeletal system disorder (196) Hereditary disease (172) Bone disorder (47) Human disease (14) Bone remodeling disease (5) Skeletal system disorder (4) Disease of genetic or genomic mechanism (2) Hyperostosis (2) Craniometaphyseal dysplasia (1)
Trials to join now! 17 Not yet recruiting 6 Not yet finished but already full! 4 Completed 7 Terminated 1
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  • Scientists gather leftover surgical tissue to unlock secrets of bone disease

    Knowledge-focused Terminated

    This study collected bone, cartilage, skin, and fat tissue from 50 patients undergoing surgery at Children's National Medical Center. The goal was to grow cells from these tissues in the lab and analyze them to better understand bone and connective tissue diseases. The study was …

    Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) • Aim: Knowledge-focused

    Last updated Jun 27, 2026 07:52 UTC

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