Cowden disease
MONDO:0016063A genodermatosis characterized by the presence of multiple hamartomas in various tissues and an increased risk for malignancies of the breast, thyroid, endometrium, kidney and colorectum. When CS is accompanied by germline PTEN mutations, it belongs to the PTEN hamartoma tumor syndrome (PHTS) group.
Also known as: Cowden disease, Cowden syndrome, Cowden's disease, multiple hamartoma syndrome, CD, MHAM, dysplastic gangliocytoma of cerebellum
17 clinical trials for this condition and its sub-types.
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Broader categories
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New study tracks cancer risk in rare genetic condition
Knowledge-focused TerminatedThis study follows 430 people with Cowden's disease (a PTEN gene mutation) to better understand their risk of developing cancer. Researchers will track how many participants get cancer over time. The goal is to improve monitoring and care for this high-risk group.
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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AI vs. skin doctors: who diagnoses better?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether artificial intelligence (AI) can match a dermatologist's diagnosis when a general practitioner sends in photos and questions about a patient's skin condition. Researchers will compare the AI's diagnosis to the dermatologist's for about 1000 adults. The…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC