Congenital heart defects, multiple types, 2

This pilot study tests whether putting back a child's own thymus tissue during heart surgery is safe and helps support the immune system. In some congenital heart disease surgeries, the thymus is removed to reach the heart, which may weaken immunity. Researchers will compare chil…

This trial tests whether adding a blood-filtering device, called hemoadsorption, to the heart-lung machine can reduce harmful inflammation in children undergoing complex open-heart surgery. The device is designed to remove inflammatory proteins, known as cytokines, from the blood…

This trial tests whether a personalized exercise program before heart surgery can improve physical fitness in adults with congenital heart disease. Participants are randomly assigned to either usual care or a 6-week prehabilitation plan with aerobic, breathing, and strength exerc…

Researchers in Qinghai Province, China, are testing whether artificial intelligence can help primary care doctors spot congenital heart disease during school-based screening. Schools are randomly assigned to either standard listening with a stethoscope or listening plus AI analys…

Researchers at Assiut University Hospitals are studying how well fetal heart scans before birth match the heart diagnoses babies receive after delivery. The study includes pregnant women referred for fetal echocardiography and newborns with confirmed critical congenital heart dis…

This study enrolls children and young adults scheduled for heart surgery or catheterization under general anesthesia. Researchers place a forehead sensor that measures tissue oxygen levels and use an algorithm to estimate blood hemoglobin. The goal is to see if this noninvasive m…

This study will check how accurate chest X-rays are at finding congenital heart disease in newborns. Researchers will study 60 babies in the NICU who show signs of heart problems. Each baby gets a chest X-ray within 24 hours and an echocardiogram within 72 hours. By comparing the…

Children scheduled for angiography often feel anxious, which can affect their heart rate, blood pressure and cooperation during the procedure. This trial tests whether a short virtual reality guided breathing exercise, delivered through a headset showing calming scenery, can redu…

This observational study tests whether a new device, the SpectroCor Tissue Oxygenation Monitor, can accurately track oxygen levels in the heart muscle of children undergoing open-heart surgery. The device uses a sensor placed on the heart to measure oxygen availability during key…

This study will test a handheld device called IntraOx that uses light to measure oxygen levels in heart and liver tissue during complex heart surgery in children. The goal is to see if it can give surgeons useful information about blood flow without interfering with the operation…

This study looks at how the antibiotic cefazolin spreads in the chest tissue of 10 children after heart surgery for congenital heart disease. A small probe placed during surgery will measure drug levels over 36 hours. The goal is to create a computer model to help doctors give th…

This study will test a new, non-invasive ultrasound technique that captures brain blood flow in real time for infants with congenital heart disease. Researchers aim to understand how medical treatments and surgeries affect the brain, potentially explaining why some children later…