Complex neurodevelopmental disorder with motor features
MONDO:0100516A complex neurodevelopmental disorder that involves more than one phenotype associated with the central nervous system, including but not limited to intellectual disability, autism, and seizures (epilepsy). Additionally, the disorder features at least one phenotype associated with motor function, including but not limited to spasticity, hypo- or hypertonia, dyskinesia, choreo-athetosis, or ataxia.
11 clinical trials for this condition and its sub-types, 1 tagged with Complex neurodevelopmental disorder with motor features itself.
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Browse by category →Sub-types of Complex neurodevelopmental disorder with motor features
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CACNA1A-related complex neurodevelopmental disorder 1 trial · 9 incl. sub-types
4 sub-types
- Spinocerebellar ataxia type 6 9 trials
- Developmental and epileptic encephalopathy, 42 1 trial
- Episodic ataxia type 2 1 trial
- Migraine, familial hemiplegic, 1 1 trial
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Hope for ataxia: experimental drug shows promise in Late-Stage trial
Disease control CompletedThis study tested a drug called troriluzole in 141 adults with spinocerebellar ataxia, a rare disease that affects balance and coordination. Participants took either the drug or a placebo daily for 8 weeks. The main goal was to see if troriluzole could improve symptoms like walki…
Phase 2/3 • Sponsor: Biohaven Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New keyboard designs aim to boost typing speed for people with movement challenges
Symptom relief CompletedThis study compares different visual keyboard layouts to see which helps people with complex sensorimotor disabilities type faster and with less fatigue. Twelve adults who already use a virtual scanning keyboard will test each layout. The goal is to find the best design to improv…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jul 18, 2026 00:00 UTC
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New parent support programme shows promise for families of children with complex needs
Symptom relief CompletedThis pilot study tested a community-based group programme called 'Encompass' for parents of children under 5 with complex neurodisability. Fifteen parents in East London attended ten group sessions over six months. The study aimed to see if the programme was feasible and acceptab…
Sponsor: City, University of London • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Hunting for the first clues of a devastating brain disease
Knowledge-focused CompletedThis study follows people who have a 50% chance of inheriting a gene for spinocerebellar ataxia, a group of progressive brain disorders that affect movement and coordination. The goal is to identify the earliest clinical signs and biological markers that appear before the disease…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC