Hope for ataxia: experimental drug shows promise in Late-Stage trial
NCT ID NCT02960893
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called troriluzole in 141 adults with spinocerebellar ataxia, a rare disease that affects balance and coordination. Participants took either the drug or a placebo daily for 8 weeks. The main goal was to see if troriluzole could improve symptoms like walking and hand movements, as measured by a standard ataxia rating scale.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CNS Trial
Long Beach, California, 90806, United States
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Columbia University
New York, New York, 10032, United States
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Emory University
Atlanta, Georgia, 30329, United States
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Harvard University (Beth Israel Deaconess Medical Center)
Boston, Massachusetts, 02215, United States
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Harvard University (Massachusetts General Hospital)
Boston, Massachusetts, 02114, United States
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Houston Methodist Research Center
Houston, Texas, 77030, United States
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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St. Joseph's Hospital and Medical Center
Phoenix, Arizona, 85013, United States
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University of California, Los Angeles
Los Angeles, California, 90095, United States
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University of California, San Francisco
San Francisco, California, 94158, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Colorado Denver
Denver, Colorado, 80045, United States
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University of Florida
Gainesville, Florida, 32611, United States
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University of Michigan
Ann Arbor, Michigan, 48105, United States
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University of Rochester Medical Center
Rochester, New York, 14642, United States
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University of South Florida
Tampa, Florida, 33612, United States
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University of Texas Southwestern
Dallas, Texas, 75390, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can brain stimulation tame ataxia?
- New hope for SCA patients: expanded access to investigational drug troriluzole
- Could a drug slow rare brain disease? new study uses Real-World data to find out
- New drug could slow rare brain disease that steals balance
- Scientists build giant DNA library to crack ataxia mysteries
- Smartphone app could reveal how exercise helps the brain in rare movement disorder