New drug trial aims to slow progression of rare movement disorder
NCT ID NCT03701399
Summary
This study is testing whether a daily medication called troriluzole can help slow the worsening of movement, balance, and speech problems in adults with inherited spinocerebellar ataxia (SCA). About 300 participants with specific types of SCA will take either troriluzole or a placebo pill for 48 weeks to see which group shows less decline in their ability to perform daily activities. The main goal is to see if the drug can help people maintain their current function longer.
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Contacts and locations
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Locations
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Barrow Neurological Institute
Phoenix, Arizona, 85013, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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CNS Trials
Long Beach, California, 90806, United States
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Central South University Xiangya Hospital
Changsha, Hunan, 410008, China
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Columbia University
New York, New York, 10032, United States
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Duke University Movement Disorders Clinic
Durham, North Carolina, 27705, United States
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Emory
Atlanta, Georgia, 30329, United States
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Houston Methodist
Houston, Texas, 77030, United States
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Johns Hopkins Medicine
Lutherville, Maryland, 21093, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mayo Clinic Florida
Jacksonville, Florida, 32224, United States
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Northwest Neurology, Ltd.
Rolling Meadows, Illinois, 60008, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Swedish Health Services
Seattle, Washington, 98122, United States
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UCLA
Los Angeles, California, 90095, United States
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UCSF
San Francisco, California, 94158, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Colorado Hospital
Aurora, Colorado, 80045, United States
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University of Florida Health
Gainesville, Florida, 32610, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19107, United States
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University of South Florida
Tampa, Florida, 33612, United States
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West China Hospital of Sichuan University
Chengdu, Sichuan, 610041, China
Conditions
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