Compartment syndrome

This study tests whether injecting Botox into leg muscles can reduce pain during exercise in people with chronic exertional compartment syndrome (CECS). Fifty adults with confirmed CECS will receive either Botox or a placebo injection. Researchers will track pain levels and leg f…

This study compares two treatments for chronic leg pain caused by compartment syndrome: physiotherapy (with a focus on changing running style) and surgery (fasciotomy). The goal is to see if physiotherapy works as well as surgery, which could help more people avoid an operation. …

This study tests whether a one-time Botox injection into the side abdominal muscles, given 3-7 weeks before surgery, helps surgeons fully close large ventral hernias. About 188 adults will be randomly assigned to receive Botox or a placebo, and neither they nor their doctors will…

This study looks at whether a small pressure sensor placed in the leg during surgery can help doctors spot a rare but serious problem called acute compartment syndrome. Teens aged 10 to 21 with a broken shinbone will have the sensor monitor pressure for at least 18 hours after th…

This study looks at how changing the air pressure in a patient's lungs during a tummy tuck (abdominoplasty) affects their breathing after surgery. Researchers will measure lung pressure before and after the surgeon tightens the belly muscles, and then check lung function afterwar…

This study tests a new device that continuously measures pressure in the leg to detect a dangerous condition called compartment syndrome in patients on ECMO. ECMO patients are often sedated and cannot report symptoms, making diagnosis difficult. The device may help doctors diagno…