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Cleft lip
MONDO:0004747A congenital abnormality consisting of one or more clefts (splits) in the upper lip, which may be accompanied by a cleft palate; it is the result of the failure of the embryonic parts of the lip to fuse.
Also known as: cheiloschisis, cleft lip, cleft lip (disease), cleft lip, unilateral, complete, labium leporinum
29 clinical trials for this condition and its sub-types.
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Broader categories
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Before surgery, speech lessons for cleft palate babies?
Symptom relief Not yet recruitingThis study tests whether teaching speech and language skills to infants with unrepaired cleft palate can improve their communication before palate repair surgery. Two hundred infants aged 6 to 10 months will join weekly coaching sessions with their families. The goal is to see if…
Phase: NA • Sponsor: Old Dominion University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Tailored Pre-Surgery care may improve outcomes for babies with cleft lip and palate
Knowledge-focused Not yet recruitingThis study looks at different presurgical treatments for infants born with cleft lip and palate. These treatments help shape the mouth and nose before surgery. Researchers will compare how well each approach works, how many clinic visits are needed, and how much burden it places …
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Can we predict breathing problems in cleft surgery? new study aims to find out
Knowledge-focused Not yet recruitingThis study observes 150 infants and toddlers having cleft lip or palate repair to understand how often breathing complications occur and what factors increase risk. Researchers will use standard airway scoring tools to see if they can predict problems like laryngospasm or low oxy…
Sponsor: Marmara University Pendik Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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MRI reveals hidden speech success after late cleft palate repair
Knowledge-focused Not yet recruitingThis study will use MRI scans to see how well the palate and throat muscles work after a special surgery for cleft palate repair. The surgery uses a piece of cheek muscle to close the gap and aims to improve speech. Ten people who have not had early treatment will get the surgery…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC