Chronic recurrent multifocal osteomyelitis
MONDO:0009813Chronic non bacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), is a chronic autoinflammatory syndrome that is characterized by multiple foci of painful swelling of bones, mainly in the metaphyses of the long bones, in addition to the pelvis, the shoulder girdle and the spine.
Also known as: CNO/CRMO, CRMO, NBO, chronic multifocal osteomyelitis, chronic recurrent multifocal osteomyelitis, chronic recurrent multifocal osteomyelitis (disease), non-bacterial osteomyelitis, CMO
20 clinical trials for this condition and its sub-types.
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Could a bone drug ease pain in kids with rare inflammatory disease?
Symptom relief Not yet recruitingThis study tests whether the drug zoledronate can reduce pain in children aged 4 to 17 with chronic recurrent multifocal osteomyelitis (CRMO), a rare auto-inflammatory bone disease. The 30 participants have not responded to standard anti-inflammatory drugs. They will receive eith…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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New blood tests aim to unlock mysteries of rare inflammatory diseases
Knowledge-focused Not yet recruitingThis study aims to better understand rare autoinflammatory diseases by developing blood tests that measure inflammation markers. Researchers will analyze blood samples from 60 adults and children with these conditions. The goal is to identify specific inflammation pathways, which…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:44 UTC